Chaker-Margot, M., Werten, S., Dunzendorfer-Matt, T., Lechner, S., Ruepp, A., Scheffzek, K., Maier, T. (2022) Structural basis of activation of the tumor suppressor protein neurofibromin. Mol. Cell in press.
Werner, N., Werten, S., Hoppen, J., Palm, G.J., Göttfert, M., Hinrichs, W. (2022) The Induction Mechanism of the Flavonoid-Responsive Regulator FrrA. FEBS J. 289, 507-518.
Shikura, N., Darbon, E., Esnault, C., Deniset-Besseau, A., Xu, D., Lejeune, C., Jacquet, E., Nihiri, N., Sago, L., Cornu, D., Werten, S., Martel, C., Virolle, M.-J. (2021) The Phosin PptA Plays a Negative Role in the Regulation of Antibiotic Production in Streptomyces lividans. Antibiotics 10, 325.
Lejeune, C., Abreu, S., Chaminade, P., Dulermo, T., David, M., Werten, S., and Marie-Joelle Virolle, M.-J. (2021) Impact of Phosphate Availability on Membrane Lipid Content of the Model Strains Streptomyces lividans and Streptomyces coelicolor. Front. Microbiol. 12, 216.
Palm, G.J., Buchholz, I., Werten, S., Girbardt, B., Berndt, L., Delcea, M., Hinrichs, W. (2020) Thermodynamics, Cooperativity and Stability of the Tetracycline Repressor (TetR) upon Tetracycline Binding. Biochim. Biophys. Acta Proteins Proteom. 1868, 140404.
Werten, S., Rustmeier, N.H., Gemmer, M., Virolle, M.-J., Hinrichs, W. (2019) Structural and Biochemical Analysis of a Phosin from Streptomyces chartreusis Reveals a Combined Polyphosphate- and Metal-Binding Fold. FEBS Lett. 593, 2019-2029.
Brown,P., RELISH Consortium, Zhou,Y. (2019) Large Expert-Curated Database for Benchmarking Document Similarity Detection in Biomedical Literature Search. Database 2019, article ID baz085.
Werten, S., Schneider, J., Palm, G.J., Hinrichs, W. (2016) Modular Organisation of Inducer Recognition and Allostery in the Tetracycline Repressor. FEBS J. 283, 2102-2114.
Werten, S., Kohler, C., Bayer, N., Steinmetz, I., Hinrichs, W. (2016) Structural Analysis and Knock-Out of a Burkholderia pseudomallei Homolog of the Human Transcription Coactivator PC4. Gene 577, 140-147.
Zühlsdorf, M., Werten, S., Klupp, B.G., Palm, G.J., Mettenleiter, T.C., Hinrichs, W. (2015) Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease. PLoS Pathog. 11, e1005045.
Werten, S., Dalm, D., Palm, G.J., Grimm, C.C., Hinrichs, W. (2014) Tetracycline Repressor Allostery Does Not Depend on Divalent Metal Recognition. Biochemistry 53, 7990-7998.
Xu, D., Waack, P., Zhang, Q., Werten, S., Hinrichs, W., Virolle, M.-J. (2014) Structure and Regulatory Targets of SCO3201, a Highly Promiscuous TetR-Like Regulator of Streptomyces coelicolor M145. Biochem. Biophys. Res. Commun. 450, 513-518.
Werten, S. (2013) Identification of the ssDNA-binding protein of bacteriophage T5: implications for T5 replication. Bacteriophage 3, http://dx.doi.org/10.4161/bact.27304.
Steigemann, B., Schulz, A., Werten, S. (2013) Bacteriophage T5 Encodes a Homolog of the Eukaryotic Transcription Coactivator PC4 Implicated in Recombination-Dependent DNA Replication. J. Mol. Biol. 425, 4125-4133.
Michalek, M., Salnikov, E.S., Werten, S., Bechinger, B. (2013) Membrane Interactions of the Amphipathic Amino Terminus of Huntingtin. Biochemistry 52, 847-858.
Vidovic, V., Prongidi-Fix, L., Bechinger, B., Werten, S. (2009) Production and Isotope Labeling of Antimicrobial Peptides in Escherichia coli by Means of a Novel Fusion Partner That Enables High-Yield Insoluble Expression and Fast Purification. J. Pept. Sci. 15, 278-284.
Bechinger, B., Bertani, P., Werten, S., Moraes, C.M., Aisenbrey, C., Mason, A.J., Perrone, B., Prudhon, M., Sudheendra, U.S., Vidovic, V. (2009) The Structural and Topological Analysis of Membrane Polypeptides by Oriented Solid-State NMR Spectroscopy: Sample Preparation and Theory. In: Membrane-Active Peptides: Methods and Results on Structure and Function, Castanho, M. (editor), IUL Press, International University Line, La Jolla.
Papai, G., Tripathi, M.K., Ruhlmann, C., Werten, S., Crucifix, C., A.J., Weil, P.A., Schultz, P. (2009) Mapping the Initiator Binding TAF2 Subunit in the Structure of Hydrated Yeast TFIID. Structure 17, 363-373.
Bechinger, B., Bertani, P., Marquette, A., Mason, A.J., Nedelkina, S., Perrone, B., Prudhon, M., Salnikov, E., Vidovic, V., Werten, S., Aisenbrey, C. (2008) Biophysical Investigations of Membrane-Associated Polypeptides by Solid-State NMR: Applications to Proteins and Peptides Involved in Apoptosis, Channel Formation, Antimicrobial Action and Transfection of Nucleic Acids. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, 46-COLL.
Werten, S., Moras, D. (2006) A Global Transcription Cofactor Bound to Juxtaposed Strands of Unwound DNA. Nat. Struct. Mol. Biol. 13, 181-182.
Thuault, S., Gangloff, Y.-G., Kirchner, J., Sanders, S., Werten, S., Romier, C., Weil, P.A., Davidson, I. (2002) Functional Analysis of the TFIID-Specific Yeast TAF4 (yTAFII48) Reveals an Unexpected Organisation of Its Histone Fold Domain. J. Biol. Chem. 277, 45510-45517.
Werten, S., Mitschler, A., Romier, C., Gangloff, Y.-G., Thuault, S., Davidson, I., Moras, D. (2002) Crystal Structure of a Subcomplex of Human TFIID Formed by TBP-Associated Factors hTAF4 (hTAFII135) and hTAF12 (hTAFII20). J. Biol. Chem. 277, 45502-45509.
Fribourg, S., Romier, C., Werten, S., Gangloff, Y.G., Poterszman, A., Moras, D. (2001) Dissecting the Interaction Network of Multiprotein Complexes by Pairwise Coexpression of Polypeptides in E. coli. J. Mol. Biol. 306, 363-373.
Gangloff, Y.G., Romier, C., Thuault, S., Werten, S., Davidson, I. (2001) The Histone Fold Is a Key Structural Motif of Transcription Factor TFIID. Trends Biochem. Sci. 26, 250-257.
Gangloff, Y.G., Werten, S., Romier, C., Carré, L., Poch, O., Moras, D., Davidson, I. (2000) The Human TFIID Components TAF(II)135 and TAF(II)20 and the Yeast SAGA Components ADA1 and TAF(II)68 Heterodimerize to Form Histone-Like Pairs. Mol. Cell. Biol. 20, 340-351.
Werten, S., Romier, C., Birck, C., Poch, O., Ruff, M., Mengus, G., Lavigne, A.C., Davison, I., Moras, D. (1999) Crystallographic Studies of Histone-Like Subunits of TFIID. Acta Crystallogr. A, 55, 312-312.
Werten, S., Wechselberger, R., Boelens, R., Van der Vliet, P.C., Kaptein, R. (1999) Identification of the Single-Stranded DNA Binding Surface of the Transcriptional Coactivator PC4 by NMR. J. Biol. Chem. 274, 3693-3699.
Werten, S., Stelzer, G., Goppelt, A., Langen, F.W.M., Gros, P., Timmers, H.Th.M., Van der Vliet, P.C., Meisterernst, M. (1998) Interaction of PC4 with Melted DNA Inhibits Transcription. EMBO J. 17, 5103-5111.
Werten, S., Langen, F.W.M., Van Schaik, R., Timmers, H.Th.M., Meisterernst, M., Van der Vliet, P.C. (1998) High-Affinity DNA Binding by the C-Terminal Domain of the Transcriptional Coactivator PC4 Requires Simultaneous Interaction with Two Opposing Unpaired Strands and Results in Helix Destabilization. J. Mol. Biol. 276, 367-377.
Brandsen, J., Werten, S., Van der Vliet, P.C., Meisterernst, M., Kroon, J., Gros, P. (1997) Crystal Structure of the C-Terminal Domain of Positive Cofactor PC4 Reveals a Dimeric ssDNA Binding Site. Nat. Struct. Biol. 4, 900-903.
Wijmenga, S.S., Heus, H.A., Werten, S., Van der Marel, G.A., Van Boom, J.H., Hilbers, C.W. (1994) Assignment Strategies and Analysis of Cross-Peak Patterns and Intensities in the Three-Dimensional Homonuclear TOCSY-NOESY of RNA. J. Magn. Reson. B 103, 134-141.
Lucasius, C.B., Werten, S., Van Aert, A.H.J.M., Kateman, G., Blommers, M.J.J. (1991) Conformational Analysis of DNA Using Genetic Algorithms. Lect. Notes Comput. Sci. 496, 90-97.